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Wax anatomical models designed to train physicians and educate the public were once innovative educational teaching aids. Some world-class museums including La Specola in Pisa, Josephinum in Vienna, Palazzo Poggi in Bologna, Science Museum in London, Semmelweis Museum in Budapest, Muséum national d'Histoire naturelle in Paris are proud of their collections. This amazing craft, combining art and science, anatomy and chemistry, practical skill and theoretical knowledge, which stood at the forefront of innovation in the 17th and 18th centuries, originated and flourished in Northern Italy